A reusable tamper indicating bag closure for transporting most items in a bag such as documents and portable computing devices including laptops, PDAs, mobile phones, iPods® . . . etc. that would appeal to a broad spectrum of customers including the individual buyer, the business user, and the government user. The tamper-evident bag closure is defined by a lid with multiple hasps and a base with knobs that attach to the bag and is secured by a locking mechanism placed through an opening on the base and inserted within an insertion aperture such that locking the lock mechanism causes the lid to slide into alignment with the base and engages the plurality of hasps with the plurality of knobs thus securing the bag. The bag closure also has several tamper indicating features including the use of tamper indicating markers, wire seals and tamper indicating labels.