Maryland's Defense Patent Database

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Silica mesoporous aerogels having three-dimensional nanoarchitecture with colloidal gold-protein superstructures nanoglued therein

Patent image
NRL

This disclosure describes the first viable non-enzyme protein encapsulated within an aerogel. In this, a large excess of cyt c is added to a commercial buffered Au sol solution ( ) which results in the formation of a gold˜protein-protein superstructure in the absence of separation techniques which destroy the superstructure. The gold˜protein-protein superstructure is then nanoglued into a silica framework during the sol to gel transition. To form the gel, the Au˜cyt. c superstructure in buffered medium is added to a silica sol and the composite gels are washed with acetone followed by liquid carbon dioxide and then supercritically dried to form the aerogel.The biocomposite aerogels have a multiplicity of applications particularly in the realm of sensing and energy transformation.

Inventors: 
Rolison, Debra R.; Wallace, Jean M.; Pietron, Jeremy J.; Rice, Jane K.; Stroud, Rhonda M.
Patent Number: 
Technical domain: 
Biotechnology and Healthcare
FIle Date: 
2004-08-18
Grant Date: 
2007-07-03
Grant time: 
1,049 days
Grant time percentile rank: 
19
Claim count percentile rank: 
3
Citations percentile rank: 
1
'Cited by' percentile rank: 
1
Assignee: 
US NAVY