A reusable tamper-evident security device for use on a door or container includes a pair of base members, a pair of first leg members, a pair of second leg members, a pair of U-shaped upper members, and a pair of removable security label blanks. A base member, a first leg member, a second leg member, and a U-shaped upper member are abutted, form an inner cavity between the base member and the U-shaped upper member. At least one mounting hole is provided to affix the base member to the door or container. A first guide and a parallel second guide extent perpendicularly from the top surface of the base member, allowing the removable security label blank to be slidably inserted. The U-shaped upper member abutting each base member is oriented to form an oblong shape when the two base members are adjacent the other. An optional security label may be applied to the removable security label blank.